![]() “Imagine a patient with a gastrointestinal condition running to the bathroom in the middle of the night. “Passively collected measures are powerful because nobody wants to fill in a survey,” says Andy Coravos, CEO of HumanFirst. Digital biomarkers can help gather rich data about patients, passively and remotely. It would be tough to collect enough data for drug approval based on such sparse measures. Let’s say a clinical trial collects blood sugar readings from patients who visit the clinic every month. Four reasons why digital biomarkers are game-changers “Today, we have many such digital biomarkers emerging for research and clinical use, such as keystroke dynamics, voice, eye tracking, facial recognition, smell, and gait,” says Richie Bavasso, Co-Founder and CEO of nQ Medical. For example, voice signals from a smartphone’s microphone can detect mild cognitive impairment due to Alzheimer’s disease. Additionally, scientific evidence needs to show that the health attribute measured by the device maps consistently and accurately to a clinical outcome. ![]() The measures must be objective, quantifiable, and reproducible. When can such novel health measures function as medical biomarkers? Fitbit trackers use sensors such as accelerometers to tell how many steps we’ve taken in a day or how fast we’ve been walking. Modern digital devices measure several health parameters. Common examples include blood pressure readings, heart rate, and even genetic test results. What are biomarkers? They are medical signals that can measure health in an accurate and reproducible way. Smart devices and wearables are all around us getty
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![]() ![]() Here then, are the 13 most expensive Macallan whiskies so far. Their whiskies have been known for breaking records when it comes to price both on a personal level (‘how much did you say the 15 year old was’) and at auction. That may give you a little bit of sticker shock, but if you buy one, just tell yourself you’re making an investment. Macallan - Double Cask Gold Whisky Size: 70cl ABV: 40.00 149.44 (£129. The Macallan is one of the most expensive whisky brands in existence. The octogenarian expression will be limited to just 288 decanters, each of which carries a $125,000 price tag. Best Overall Scotch: The Macallan Sitting at the pointy end of our list of one of the all-time greats, The Macallan.About as close to smooth and balanced perfection as top-shelf Scotch Whisky can get, the brand has unique expressions up and down the price spectrum, including the most expensive whisky ever sold. “The expression encapsulates the spirit of The Macallan and the timeless nature of our mastery and craftsmanship.”Īs you might imagine, The Macallan’s oldest single malt won’t come cheap. Over the past four decades, Macallan has built probably the best reputation for quality malt whisky rare expressions can change hands for thousands of pounds, and prices for such bottles are continuously going up. “It’s hard to put into words how truly special this whisky is,” Campbell told Forbes earlier this week. Macallan is the most sought-after whisky for collectors, and here you'll find a huge range of Macallan Scotch whisky to buy online. The Macallan is one of the first legally licensed distilleries in Scotland, founded in 1824. ![]() One hand represents the distillery’s workers in 1940, another one-time chairman Allan Shiach and the last current master whiskey maker Kirsteen Campbell. Up until now, The Macallan’s oldest whisky had been a 78-year-old single malt, which, as Food & Wine points out, was the world’s oldest until Glenlivet announced an 80-year-old last year. The hand-blown glass vessel comes cradled by a bronze-cast statue featuring three hands. Just as impressive is the unique decanter the scotch comes in. Its taste profile combines an array of flavors, including dark chocolate, peat and ginger, and it has a smoky note that is subtle but unmistakably the work of the distillery. Over the next 81 years the single malt took on a rich amber hue. Whisky Foundation will never pass any personal information on to any third party apart from aforementioned “service providers.” Unless you check the box instructing your browser to remember your username and password these cookies will be deleted when you close your browser.The Reach was first poured into a sherry cask way back in 1940. ![]() This information is needed in order to make your visit simple and more efficient. The Macallan Distillers Ltd is a wholly owned subsidiary of Edrington, which purchased the brand from Highland Distillers in 1999. In addition, when placing an order the cookies will capture your first and last names, your email address and your customer ID. Primarily we use cookies for the sole purpose of monitoring traffic, e.g., the IP address from which you access the site the location (country) from which you access the site the type of browser and operating system used to access the site the date and time of your access to the site the pages you visit the Internet address of the website from which you accessed the site to log repeat visitors for statistical and analytical purposes to track interaction with online advertising (e.g., to monitor the number of times that a banner ad is displayed and the number of times it is clicked) and to compile and report to third parties aggregate statistics about our users in terms of numbers, traffic patterns and related site information.Ģ. Like most websites, this site uses “cookies” (small data files that our server sends to your browser when you visit the site) to gather and store information about your visit to our website. ![]() After a few emails back and forth, we have been told that their system is availble, and in process for release to the US. After contacting a few manufacturers of such controllers, we learned that it will be some months before we will see a product for this bike, except for one. From this point we have entered yet another ![]() If we were to then be able to adjust the ignition timing, we could potentially see even more gains, perhaps significant. If we were to adjust the fueling, one could guess that on an engine this size, we could see an additional With that said, let's look at what we can now improve from this information. Yoshimura takes the time and effort to appropriately tune their systems, so keep that in mind when you are looking for options. Speak for other brands and manufacturers. But most importantly, it is not so much where a tuning would be a requirement if you wanted to use this exhaust. Running a little lean, but consistent across the entire range. ![]() Holy cow!! A gain of 4.5 horsepower and 2.2 ft-lbs of torque! That is 7% and 5%, respectively, over the stock system! All from a simple exhaust swap. I was definitely impressed with what I gained from so little investment. Was reduced when rolling on the throttle making for a much more forgiving experience. I could tell there was a bit more pick up in throttle response, and not only that, but the off throttle/on throttle was a much more smooth transition. It made a very noticeable difference from the very moment I hit the How does it sound and what are the gains? Watch the below video for my first ride impression. I couldn't justify spending the extra money for just a little more weight loss.Īfterall, this isn't a race bike. This thing looks great on the bike! I went with the regular stainless system with carbon tip. ![]() Is needed to change the factory system as demonstrated in this video HERE. I couldn't wait to get home and throw this thing on! The installation was quick and simple. It was just a matter of final production until I would have this beautifulĪnd then it came!!!! The excitement was more than I could bare. Released dyno sheets on gains, and comparison video between stock and the Alpha, they were miles ahead of everyone else. The R&D team know what they are doing when it comes to race exhausts. Everything was still in development having the kinks worked out. With Freddy's raceĮxperience and business relationships to various vendors, it was decided to start with exhaust and give the Yoshimura Alpha a try. With the knowledge the guys at Superbike Unlimited have, (displayed by the numerous trophies on the wall, and race bikes in the garage) I was ready to listen. A smooth and linear powerband, with consistent torque at all ranges. Outcome was decent, with proof of what I had felt while riding. After discussing a few options, we decided to do a basline dyno of the 2017 Z650. Was looking to do and asked if they could point me in the right direction. I walked in and explained to them what I had, what I Luckily for me, the race group and super bike shop, Superbike Unlimited, is only a few minutes away. After a short period of haggling over the price, weĬame to an agreement, exchanged the needed items, and homebound we went! I knew then, she was coming home with me. Nice and slim, the seat even lower than that of the SV650, and just the right angle on the handlebars. Everything just seemed to mesh to my person. That feeling you get, when all feels right in the world, and two seem as one. Redesign of the popular ER6 series of bikes that has a huge following overseas. He pointed me in the direction of the all new addition to the Kawasaki stable. Specs were done, he asked me if I had seen or heard of Kawasaki's new Z650. Once a thorough look over, sit on, and run down of the I informed him on what I was thinking, and he then guided me to exactly what I THOUGHT I was going to buy. After spending a few minutes looking around, a saleman approached Surely no one in their right mind would want to take a motorcycle home on a day like this? Oh, but there was. On the day I walked into the dealership, it was a Little did I know that fate had other intentions. A nice compromise between a cruiser and true sport bike. A capable bike, agile, low seat height, and comfortable "sport" riding I was in the market for a new bike, and had put my eye toward the new Suzuki SV650. ![]() Chacmools are often associated with the Aztec rain god Tlaloc or with the similar Mayan rain god Chac (or Chaac). ![]() Chacmools have been found throughout central Mexico and the Yucatan, down into Central America. His hands are on his abdomen, holding a dish or a bowl for accepting ritual offerings. “Chac Mool” was first published in Los Dias Enmascarados in 1954, then again in the 1973 collection Chac Mool y otros cuentos ( Chac Mool and other stories - also never translated).Ī chacmool is a particular form of Mesoamerican sculpture: a figure of a man reclining on his back, upper body supported by his elbows and knees bent. Sure enough, a little digging uncovered an English rendering of the short story “ Chac Mool“, translated by Jonah Katz, currently a professor of phonetics and linguistics at West Virginia University. But hope springs eternal, and so I had to look around…. Given the general preference of the reading public for novels over short stories, I’m not surprised, and such early writing would probably be considered only a minor work of his - not the optimal candidate for the effort of translation. In fact, his first book was a collection of fantastic fiction called Los Dias Enmascarados ( The Masked Days), which, to my knowledge, was never translated into English. One of the things I’ve learned in my reading is that Carlos Fuentes wrote quite a few short stories. I’ve been awash in translations of Spanish-language literature lately (more on that in a future article) it’s been fascinating reading. ![]() ![]() Need some advice about an IT setup Databases.Now in present situation, the wire goes out from 1s. Earlier i was using net only in the upper floor, so been using the wire for years indoors. dont know much.I am using my cat 5e wire as an extension for the router in ground floor. Does cat 5e require some shielding if exposed to sun? Networking.I would use Sysinternals Process Monitor Opens a new window and also TCPView Opens a new window to see what is going on. I would certainly uninstall the KB3002657. Who knows what kind of leftovers are there. Disable both during the installation.ĭelete also content of \Tmp and \Temp. Maybe firewall and/or antivirus are interfering with the registration process. It could also be that DraftSight can't write into some registry key due to insufficient permissions or the key is read only although you are logged on as administrator. It freezes while reading registry entries for the Internet connection and will never make the connection. Flash Player update suffers from this sometimes. My feeling about what you have described would fall into following possible issues.ĭraftSight is not for some mysterious reasons reading Internet connection informations. And If you think I am missing a step or something to resolve this I would greatly appreciate it! Thank you very much ![]() If anyone has any knowledge of this, or had a simular issue with this please let me know. But just for kicks, I used a wifi dongle and connected to my T-mobile data and tried the process that way as well, still no luck, same issue. The above steps usually always fix the issue for me. As i do these installations daily and have over 200 users and no one has had this issue before, Nor have I seen it. exe files, rebooted, reinstalled, rebooted.ĥ) I used known good registry cleaners to take out what was left of Draftsight on the entire machine.Īlso while searching I should mention, that alot of people had issues with it being a problem with the proxy server on the network or through the ISP, this can't possibly be the issue for me. Neither of which worked.ģ) Located Draftsight within C:/users/*****/appdata/roaming/draftsight, and cut and pasted to just C:Ĥ) I did all of these at once, Uninstalled,rebooted the machine, disconnected from the network, deleted keys, Relocated the. The time on the professional is up, and Draftsight has reverted to the original issue of not activating the free version.ġ) Made sure user had local admin rights, uninstalled the program, reinstalled same issue.Ģ) I have uninstalled program, went to registry editor, found the SWactivation key and deleted it and 2nd attempt renamed it to _OLD. This was about a month ago, so after troubleshooting and no resolution I gave the User the free 30 day trial period for Professional to buy myself some more research time. This message will never appear nor will I ever get the Email. Once this has been done, Draftsight is supposed to give you a message saying an email has been sent to finish activation. Basically, it will ask for activation then I will enter in the information required. I have never seen this before, simular but not this. Upon further review he was correct and I have activated many draftsight's seeing as we have over 200 users. User reported that everytime draftsight is opened it will ask him for activation. Let me provide the original issue before I tell you the troubleshooting steps I have already taken. I have researched and researched over and over. Okay so I am having a bit of a problem with draftsight and I am getting nowhere with the draftsight "professionals". ![]() The ID code for each arrangement is printed on the back, just to the right of the team art next to Sweet Cheat (appropriate!). Becoming mischievous little robots that love to have fun. One of the BotBots is a robot that transforms into the Autobot logo/symbol. SIMBL-related files can be found either in /Library/Application Support/SIMBL/Plugins or /Library/Application Support/SIMBL/Plugins. Causing the various objects in said mall to come to life. SIMBL is not a part of Apple's Mac OS X package, but is an extension that can be used by other developers in their own work to extend applications where they may not have the original source code (like Safari). The basic idea behind the line is that an Energon storm cloud hit a mall. Hasbro released it as a blind box figurine line. While other BotBots have Autobot and Decepticon logos on them as part of their design, Ol' Tic Toc has an Autobot symbol inside their body amongst the clockwork gears molded onto them that can only be seen when you transform the legs for robot mode. In most of the packs, the eight blindpacked "controller buttons" at the bottom half have four of the redeco Arcade Renegades, with the other bubbles filled by Series 1 repacks (whose alt-modes at least fit in with the general theme of the set, being bad food and potential prizes). The Toy Line Botbots started all the way back in 2018. Bank Shot, Clawsome, Cackle Corn, Driver Ted, Greed Feed, Knotzel, Old Cool, Tutu Puffz These good bots include: Anty Farmwell the ant farm Aunt Kitty the black cat Awwooof the pet carrier Bartholomew Barkston III the pet carriage Bully Bulldog the dog collar Chow Wow the doggie food bowl Coach Husky the Siberian husky Crickets.Every pack shows the eight new-mold Renegades in the "game screen" part of the packaging, in the same position: Part of the third series of BotBots, the members of the Arcade Renegades are found only in the special "Arcade Renegade" themed 16-packs. Arcade Renegades Surprise (16-packs, 2019) Transformers Toys BotBots Series 5 Frequent Flyers 8-Pack Mystery 2-in-1 Collectible Figures Kids Ages 5 and Up (Styles and Colors May Vary) by Hasbro. ![]() Mine was a little over 90 when I trotted in-and I felt so far from prepared even then that I presume the press release’s author is either preternaturally talented or out of his mind. The press release included with my review copy recommends a character level of 65. The Old Hunters is ludicrously, painfully, torturously difficult-so difficult that its (say) ten hours were stretched out for me to an exorbitant twenty-five, much of it spent repeating arduous grinding circuits. (The personal reward for all this rigor has been exhaustively chronicled elsewhere.) That The Old Hunters is grueling should hardly seem surprising. Miyazaki’s games are so capably, even elegantly designed that their demands on the player never quite seem unfair or unreasonable, no matter how outrageous one naturally feels, as with a challenging novel, that their difficulty is conquerable. Bloodborne spiritedly advanced the cause: many of its ghastly enemies were occasion, for this player, for much hurling of the controller and gnashing of the teeth-though not at all unpleasantly. Hidetaka Miyazaki’s most enduring idea was that videogames could stand to be rather more difficult. The inclusion of so many here strikes me as nothing more than a concession to value. Bloodborne never particularly encouraged variety in arms-the blood stones needed to upgrade a weapon made it virtually impossible to enjoy the full use of more than one or two. And while nearly a dozen new weapons are introduced to your repertoire over the course of the game, only one, the Whirligig Saw, offers anything like a significant change. Combat is still very much a matter of evading and parrying, swooping in and strafing away. This cloned environment has been populated with a handful of new enemies, true, whose styles and skillsets, especially early on, afford one a good deal of novel encounters. It begins in a negligibly remodeled Odeon Chapel, now ground zero of the Nightmare from there one proceeds as usual through the Cathedral Ward, made over with verdant overgrowth and trees that slope and wend through the hills. In this way The Old Hunters feels less like an expansion than a reiteration. The Living Failures are meant to be forgiven their plagiaristic aspect because it’s part of the game’s curious design. Thus are its sundry ghouls and dreamscapes in fact reflections of the other side. And the Hunter’s Nightmare, one gathers, is a kind of mirror image of Yharnam, the city in which Bloodborne proper takes place. The Old Hunters takes place in a realm known as (what else?) the Hunter’s Nightmare. Though the resemblance may be deliberate. These fellows are rangy and grayish and sort of drably nondescript, and in their number and manner seem conspicuously similar to the Celestial Mob fought previously in the Upper Cathedral Ward they faff about in a garden rather than a shallow pool but attack alike and are contended with in much the same way. About midway through one confronts a troop of miniature bosses simply called the Living Failures, which could be the name of a good punk-rock band. Ī sense of duplication looms over The Old Hunters. ![]() They’d better leave Bloodborne alone after this expansion. The Despairing Cutlass? The Infirmary of Sorrow? You half-expect to wander into the A Bit Crestfallen Caverns or pick up a rapier called Glum. One can well imagine a brainstorming session at From Software, the developers trying to think gloomily as they thumb a dog-eared thesaurus. So too will its macabre menagerie: the Bloodlickers and the Parasites, the Winter Lanterns and the Nightmare Executioners. The River of Blood, the Beast Cutter, the Surgery Altar, the Astral Clocktower, the Blood of Adeline, the Nightmare Church, the Underground Corpse Pile, the Holy Moonlight Sword, the Beasthunter Saif: the settings and armaments that furnish The Old Hunters will certainly sound familiar to veterans of Bloodborne. ![]() The raw images were converted to FITS and then processed according to my usual CCD routine. Koornlandskloof Guest Farm, Northern Cape Province, South Africaĭark frames were acquired separately after the last exposure. Tokina 4/12-24 mm 17 mm, stopped down to f/6.3 The bright star to the right of the LMC is Canopus, the second brightest star in the night sky. The startrail image shows the Large Magellanic Cloud above the farm house (which I illuminated with a white LED flashlight). Due to its altitude and the arid climate, the night sky is of exceptional quality. Best leather jackets for men usa, Gimp tutorials photo editing 2.8. 1300 m) and run by Lampies and Aret Lambrechts. New democratic coalition 1936, Foto startrail, Transvanguardia italian. 35 km northwest of Sutherland, South Africa (32° 13' 34" S, 20° 20' 48" E, elevation approx. Now get & make others spellbound by the star trail photograph you just took.Koornlandskloof Guest Farm is located in the Roggeveld Mountains, approx. However, it is not saved by default & you need to save it manually(CTRL +S). Once done, you’ll be presented with the final composited photograph. Da dachte ich mir, dass muss aber einfacher gehen, wenn ich das nochmal machen will Read More Gimp ImageMagick Python Astro Astrophotography Startrails. Depending on the number & resolution of the photographs along-with the processing power of your computer, this process will take time. Once satisfied, hit ‘ok’ & you can go for a siesta. If you have not shot any dark frames, let the directory of dark frames be same as the one you selected for light frames. Because of the speed issue, this is disabled by default.Īs of now the plug-in works with the following file : jpg, jpeg, tiff, tif, bmp and png. This slows the process down considerably, around 3-4 times slower. Live display update (MUCH slower) : This will display the frames to the screen live as they are stacked together. They will be named trail00001.jpg, trail00002.jpg and so on. Intermediate save directory : The directory to save the intermediate frames to. Save intermediate frames : Checking this will save an image after each frame is layered, allowing you to make a time lapse of the trail building up. Use Dark Frames : Do you want to use dark frame noise reductionĭark Frames : The folder containing all your dark frames, ie the ones you took with the lens cap on. Light Frames : The folder containing all your light frames, ie the ones you can see the stars in. Now launch the startrail compositor & you should get a similar window. Make sure you restart GIMP after you’re done with changing the file permission above. This would give the necessary executable permission to the users for the file & you should be able to see the plug-in under the submenu. ![]() #chmod u+x ~/.gimp-2.6/plug-ins/startrail.py If you’re not able to see the new sub-menu, make sure the permission of the plug-in file is executable to your user. Now launch GIMP & you should find a new sub-menu by File>Create>Python-Fu>Startrail. Once downloaded, copy the plugin file to ~/.gimp-2.6/plug-ins/ directory on your machine. And you will see lots of familiar character designs from other miHoYo titles. The plugin is known as ‘ gimp-startrail-compositor‘. As for the gameplay and combat style, Honkai: Star Rail will have a turn-based system with an open world for players to explore, similar but a bit different from Genshin Impact. Here is a small GIMP plugin which will help you elevate all that pain & concentrate more on shooting part of star trails. However most of the times when it comes to post-processing the photos after shooting a star trail can be a pain. ![]() Its one of the most beautiful vista of nature. Star-trail photographs are mind boggling to look at. Shocked and crestfallen, they consulted multiple other doctors and hospitals, who in turn diagnosed the lump as not a tumor but a water cyst. ![]() When she and her son decided to walk away from their restaurant, she visited her doctor for a health checkup she was immediately diagnosed with pancreatic cancer in the summer of 2020. The longtime market on Vermont Avenue has returned after a difficult year, but can its vendors find a way to survive?Īs it happens, it was her semiretirement that began Jung Ye Jun’s journey to realizing her years-long dream of opening a chicken shop. ![]() “So this is going to be the last journey.”įood How a Salvadoran market became the soul of a community - and now fights to survive “This soup - samgyetang, ginseng chicken - is something that I’ve always wanted to do before I die,” she said. Speaking through her son, Jung Ye Jun says she feels “very good about it.” She doesn’t consider her return to the kitchen as being called back from retirement, as she’s been keeping up with banchan and seasonal samgyetang home orders since closing Jun Won in 2020, but now at 75, she says she does see Jun Won Dak as her final restaurant concept. The duo also will offer dakdoritang, a spicy chicken stew and their Jun Won signatures of galbi-jjim (braised beef short ribs) and eundaegu (braised black cod). Gradually, Jeff Jun says, they might increase the amount to 75 or 100 bowls. At Jun Won, in the season, they would sell 20 or 30 orders a day at Jun Won Dak, where the dish will be available year-round, they’ll offer 50 orders each day. ![]() It’s trussed and boiled in broth that’s already simmering, scented with Korean herbs and roots. The Juns served theirs most summers at Jun Won, and again for limited home orders after closing the restaurant, soaking the rice overnight, then adding ginseng, jujube and garlic before using it to stuff chicken. The new format and menu will center around four dishes, especially samgyetang, a stuffed-chicken soup traditionally eaten during three summer periods: the start of season (Chobok), the middle of summer (Jungbok) and the end (Malbok). We’ve got to walk away or we might even lose our house.’” It was really hard for her to admit and listen and go with it: At first she said, ‘You’re crazy,’ and I went, ‘No, that’s how it is right now. I don’t want to take that risk, so I said let’s let it go. “If I lose my mother, I’ll lose her forever. “ I thought, ‘This is our life, in our restaurant, but I think my mom’s life is a lot more important than the restaurant,’” said Jeff Jun. But with the exception of fulfilling home orders of banchan and seasonal samgyetang - a ginseng chicken soup that will be at the heart of Jun Won Dak’s menu - Jung Ye Jun was more or less out of the business due to age and concerns regarding public health, given COVID-19. Jeff Jun had planned to remain in the restaurant industry in some form, perhaps to launch a sandwich concept. ![]() The move to reopen Jun Won in any capacity is as much a surprise to Jung Ye Jun and Jeff Jun as it is to the restaurant’s fans, whose elation is already evident on social media. On this week’s episode, we try three different mandu specialists in Koreatown for some king mandu, spicy shrimp dumplings and pan-fried dumplings. Food We went on a dumpling crawl in Koreatown. ![]() Here are a few snapshots from my installation process: This air conditioner installs like most conventional window units. It also comes with a remote control that can handle all functions. This TaoTronics air conditioner has a conventional AC design with air louvers on the top front, and the filter under the front vent door. Please Make Sure the Air Filter is Completely Dry Before Reinstalling. Reusable and Washable Air Filter can be easily slid out and washed with warm water and dish soap for best performance. Quick & Easy Installation: Specially designed to fit windows (sliding up and down) from 25″ to 36″ wide with a minimum height of 13.5″, all window mounting kits are included for an easy install.With a 12.1 energy efficiency rating(EER), this energy star-certified air conditioner effectively saves energy while keeping you stay cool and comfortable on hot summer days. Low Noise & Energy-Saving: Unlike normal window air conditioners, the TaoTronics air conditioner is controlled by two independent motors, achieving the optimal balance between high performance and low noise.LED Digital Display: All Functions can be set on LED Digital Display Panel Include Fan Speed Selection, Sleep Mode, 24-Hour Timer, Energy Saver Mode, Auto Mode, and Fan Only.It’s able to remove excess moisture up to 2.43 pints per hour and provide 4 fan speeds to fit your specific needs. 3-IN-1 Functionality: This new design window air conditioner combines the functionality of air conditioning, dehumidification, and fan-only mode.Quicker & Stronger Cooling Capacity: 8000 BTU window air conditioner is powerful enough to get fast and efficient air cooling for a single bedroom or small living room up to 350sq.ft.1 x TaoTronics Window Air Conditioner 8000 BTUġ x Set of Installation Hardware Design and features |
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